Marcel Rieker

Angestellt, Founder, Merck KGaA, Darmstadt, Germany

Darmstadt, Deutschland

Fähigkeiten und Kenntnisse

antibody-drug conjugates
protein expression
peptide synthesis
antibody-drug conjugation
protein purification
basic handling of small scale chemical reactors
Sortase A
cell culture
Chromatography
cell-based assays
drug combinations
DNA-damage response
Flow Cytometry
cell viability assays
organic synthesis
enzymatic bioconjugation
bioconjugation
biochemistry
biotechnology

Werdegang

Berufserfahrung von Marcel Rieker

  • Bis heute 3 Jahre, seit Juli 2021

    Founder

    Merck KGaA, Darmstadt, Germany

  • 6 Monate, Jan. 2021 - Juni 2021

    Senior Scientist & Project Lead

    Merck KGaA, Darmstadt, Germany

  • 2 Jahre, Jan. 2019 - Dez. 2020

    Postdoctoral Researcher

    Merck Healthcare KGaA

  • 3 Jahre und 1 Monat, Okt. 2015 - Okt. 2018

    Doctoral Candidate

    Merck KGaA, Darmstadt, Germany

    Dissertation in the department ADCs and Targeted NBE Therapeutics on the identification and evaluation of synergistic drug combinations of DNA-damaging antibody-drug conjugates with DNA-damage response inhibitors for combating cancer. Title: "Targeted Combination Therapy: Discovery and Evaluation of Synergistic Anticancer Effects of Anti-HER2-Duocarmycin Antibody-Drug Conjugates Combined with ATR Inhibitors"

  • 3 Monate, Juli 2015 - Sep. 2015

    Trainee

    Merck

    Topic of the internship: "Novel antibody-drug conjugate-linkage technology: Synthesis of bioreductively cleavable linker"

  • 6 Monate, Dez. 2014 - Mai 2015

    Master Student

    Merck

    Masterthesis mit dem Thema: "Tailor-made antibody-drug conjugates: Hybrid ADCs via orthogonal biocatalysis"

  • 2 Monate, Okt. 2014 - Nov. 2014

    Trainee

    Merck

    Internship with a focus on antibody and enzyme production.

  • 11 Monate, Dez. 2011 - Okt. 2012

    Working Student

    AppliChem GmbH

    Tasks in production, but also special assignments such as putting into operation an automated filling machine.

  • 9 Monate, Aug. 2009 - Apr. 2010

    Civil Servant

    Kerckhoff Klinik GmbH

    Civil servant in the catheter lab. Tasks included making preparations for examination and taking minutes of surgeries.

  • 4 Monate, Juni 2009 - Sep. 2009

    Trainee

    MAXS GmbH

  • 2 Jahre und 1 Monat, Juli 2007 - Juli 2009

    Trainee

    MAXS GmbH

Ausbildung von Marcel Rieker

  • 5 Jahre, Okt. 2010 - Sep. 2015

    Chemie

    Technische Universität Darmstadt

    Biochemisty, Organic Chemistry, Technical Chemistry.

Sprachen

  • Deutsch

    Muttersprache

  • Englisch

    Fließend

  • Spanisch

    Grundlagen

  • Schwedisch

    Grundlagen

  • Französisch

    Grundlagen

Interessen

Mountain biking
Mountain hiking
Music

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